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Drug ReportsCanrenoate potassium
Canrenoate potassium
Canrenoate potassium is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
5D
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Events
FDA approval date
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Patent expiration date
Study first post date
Last update post date
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Completion date
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Trade Name
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EMA
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Agency Specific
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Patent Expiration
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ATC Codes
C: Cardiovascular system drugs
— C03: Diuretics
— C03D: Aldosterone antagonists and other potassium-sparing agents
— C03DA: Aldosterone antagonists
— C03DA02: Potassium canrenoate
HCPCS
No data
Clinical
Clinical Trials
22 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart failureD006333EFO_0003144I50———1—1
FibrosisD005355—————1—1
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCanrenoate potassium
INNpotassium canrenoate
Description
Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium, the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group. Like spironolactone, it is a prodrug, and is metabolized to active canrenone in the body.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
C[C@]12CC[C@H]3[C@@H](C=CC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@]2(O)CCC(=O)[O-].[K+]
Identifiers
PDB—
CAS-ID2181-04-6
RxCUI—
ChEMBL IDCHEMBL1371200
ChEBI ID—
PubChem CID23671691
DrugBankDB09015
UNII IDM671F9NLEA (ChemIDplus, GSRS)
Target
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Variants
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 303 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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651 adverse events reported
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