Canrenoate potassium
Canrenoate potassium is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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22 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | 1 | — | 1 |
| Fibrosis | D005355 | — | — | — | — | — | 1 | — | 1 |
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Epidemiology
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Drug
General
| Drug common name | Canrenoate potassium |
| INN | potassium canrenoate |
| Description | Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium, the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group. Like spironolactone, it is a prodrug, and is metabolized to active canrenone in the body.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@]12CC[C@H]3[C@@H](C=CC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@]2(O)CCC(=O)[O-].[K+] |
Identifiers
| PDB | — |
| CAS-ID | 2181-04-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1371200 |
| ChEBI ID | — |
| PubChem CID | 23671691 |
| DrugBank | DB09015 |
| UNII ID | M671F9NLEA (ChemIDplus, GSRS) |
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651 adverse events reported
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